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Project_10 Q31 StudyTitle Probing for comorbidity: evidence for other psychiatric disorders in compulsive checking
| Description: | This study (Q31) is one of a series of studies performed in the Szechtman lab at McMaster University and deposited in the FRDR public repository as a collection under the name "A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection". This collection as a whole constitutes a big dataset containing raw data objects of video, track, and path plot records of rats exploring for 55 minutes a large testing environment in a standardized paradigm during chronic treatment with psychostimulant drugs; for details of this big dataset see, https://www.frdr-dfdr.ca/repo/collection/szechtmanlab. The historical context for study Q31 was Project_10 entitled: "Probing for comorbidity". Title of the experiment in Q31 was "Effect on performance in tests of depression and anxiety by rats expressing compulsive checking". As part of the experimental design, a chronic quinpirole and a chronic saline group received 10 trials in the open field to induce compulsive checking, which was then followed by various tests of depression and anxiety. The present dataset provides raw data objects only from the open field trials. |
| Authors: | Szechtman, Henry; McMaster University;  0000-0003-3986-4482Dvorkin-Gheva, Anna; McMaster University; 0000-0001-7295-7440Tucci, Mark C.; McMaster University; Seneca College |
| Keywords: | animal model obsessive compulsive disorder OCD compulsive checking behavior exploration locomotion motor activity behavioral sensitization security motivation system male rats Long-Evans open field large testing environment 160x160 cm dopamine receptor agonist chronic treatment with quinpirole (0.5 mg/kg) repeated injections of saline vehicle video recording digitized track record plot of routes of locomotion repeated testing repeated trials per rat 10
trials available 557
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number of rats 56 |
| Field of Research: | Biological sciences > Neurosciences, biological and chemical aspects > Behavioural neuroscience of reward and motivation
Basic medicine and life sciences > Neurosciences, medical and physiological and health aspects > Neurosciences, medical and health and physiological aspects, not elsewhere classified
Psychology and cognitive sciences > Psychology, social and behavioural aspects > Psychopathology
Psychology and cognitive sciences > Cognitive sciences > Cognitive behaviour
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| Publication Date: | 2021-07-14 |
| Publisher: | Federated Research Data Repository / dépôt fédéré de données de recherche |
| Funder: | Canadian Institutes of Health Research (CIHR); Dopamine, movements, motion and behaviour: Animal model of OCD; MOP-64424 |
| URI: | https://doi.org/10.20383/102.0433 |
| Related Identifiers: |
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| Geographic Coverage: | Place Name Health Sciences Centre, McMaster University City Hamilton Province / Province / Territory Ontario Territory Country Canada |
| Geographic Point: | Latitude 43.25978 Longitude -79.91763 |
| Appears in Collections: | A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection |
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Access to this dataset is subject to the following terms:
Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
Citation
Szechtman, H., Dvorkin-Gheva, A., Tucci, M. (2021). Project_10 Q31 StudyTitle Probing for comorbidity: evidence for other psychiatric disorders in compulsive checking. Federated Research Data Repository. https://doi.org/10.20383/102.0433
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