Field
Value
Language
dc.contributor.author
Szechtman, Henry
datacite.creator.affiliationIdentifier
https://ror.org/02fa3aq29
en_US
datacite.creator.affiliation
McMaster University
en_US
datacite.creator.nameIdentifier
https://orcid.org/0000-0003-3986-4482
en_US
dc.contributor.author
Dvorkin-Gheva, Anna
datacite.creator.affiliationIdentifier
https://ror.org/02fa3aq29
en_US
datacite.creator.affiliation
McMaster University
en_US
datacite.creator.nameIdentifier
https://orcid.org/0000-0001-7295-7440
en_US
dc.date.accessioned
2021-07-14T15:03:35Z
dc.date.available
2021-07-14T15:03:35Z
dc.date.issued
2021-07-14
dc.identifier.uri
https://www.frdr-dfdr.ca/repo/dataset/9972ba15-caae-4ceb-bc7c-5e904b4a479c
dc.identifier.uri
https://doi.org/10.20383/102.0418
dc.description
This study (Q47) is one of a series of studies performed in the Szechtman lab at McMaster University and deposited in the FRDR public repository as a collection under the name "A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection". This collection as a whole constitutes a big dataset containing raw data objects of video, track, and path plot records of rats exploring for 55 minutes a large testing environment in a standardized paradigm during chronic treatment with psychostimulant drugs; for details of this big dataset see, https://www.frdr-dfdr.ca/repo/collection/szechtmanlab.
The historical context for study Q47 was Project_02 entitled: "Probing the neurochemistry of sensitization and compulsive checking". Title of experiment in Q47 was "Effect of 8OHDPAT dose (0 0.03125 0.0625 0.125 mg/kg) co-injected with a low dose of QNP (0.125 mg/kg) on the development of sensitization and compulsive checking (batch 2). Q47 was a repeat of Study Q46 (hence "batch 2" in title of experiment for Q47). For Q47, like for Q46 (dataset doi: 10.20383/102.0419), each rat received 13 trials in the open field. However, in IDStudy Q47, rats received a 14th trial in the open field, but for this test the open field was emptied of the 4 objects normally in it. This particular trial is grouped under Project_09 ("Probing the environmental modulation of sensitization and compulsive checking"), giving IDStudy Q47 a second title, "Probing the environmental modulation of sensitization and compulsive checking: influence of no objects in the open field on expression".
The historical context for IDStudy Q47 includes the introduction of "enriched" housing, that is, a piece of black plastic tube was placed in the rat's home cage (prior to this study, there were no objects in the home cage). A comparison of study Q47 with Q46 showed that "enriched" housing did not influence the development of sensitization or compulsive checking
en_US
dc.publisher
Federated Research Data Repository / dépôt fédéré de données de recherche
dc.rights
Creative Commons Attribution 4.0 International (CC BY 4.0)
en_US
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
en_US
dc.subject
animal model
en_US
dc.subject
obsessive compulsive disorder
en_US
dc.subject
OCD
en_US
dc.subject
compulsive checking behavior
en_US
dc.subject
exploration
en_US
dc.subject
locomotion
en_US
dc.subject
motor activity
en_US
dc.subject
behavioral sensitization
en_US
dc.subject
security motivation system
en_US
dc.subject
male rats Long-Evans
en_US
dc.subject
open field
en_US
dc.subject
large testing environment 160x160 cm
en_US
dc.subject
dopamine receptor agonist
en_US
dc.subject
chronic treatment with quinpirole (0.125 mg/kg)
en_US
dc.subject
serotonin receptor agonist
en_US
dc.subject
chronic treatment with 8OHDPAT (0.125 mg/kg)
en_US
dc.subject
co-injections of quinpirole and 8OHDPAT
en_US
dc.subject
dose-response study
en_US
dc.subject
repeated injections of saline vehicle
en_US
dc.subject
video recording
en_US
dc.subject
digitized track record
en_US
dc.subject
plot of routes of locomotion
en_US
dc.subject
repeated testing
en_US
dc.subject
repeated trials per rat 14
en_US
dc.subject
trials available 773
en_US
dc.subject
number of rats 56
en_US
dc.title
Project_02 Q47 StudyTitle Probing the neurochemistry of sensitization and compulsive checking: dopamine and serotonin systems
en_US
globus.shared_endpoint.name
f163c1b3-9c88-42f6-a7bb-5839ed6c4063
globus.shared_endpoint.path
/11/published/publication_413/
datacite.publicationyear
2021
datacite.contributor.ProjectManager
Sakic, Boris
datacite.date.Collected
2015-07-13/2015-08-28
datacite.resourcetype
Dataset
en_US
datacite.relatedidentifier.IsCitedBy
https://doi.org/10.1093/gigascience/giac092
datacite.relatedidentifier.Continues
https://doi.org/10.20383/102.0419
datacite.relatedidentifier.IsPartOf
https://www.frdr-dfdr.ca/repo/collection/szechtmanlab
datacite.geolocation.geolocationPoint
43.25978 -79.91763
datacite.geolocation.geolocationPlace
Health Sciences Centre, McMaster University;Hamilton;Ontario;Canada
datacite.fundingReference.funderName
Ontario Mental Health Foundation (OMHF)
en_US
datacite.fundingReference.awardNumber
Type A Grant
en_US
datacite.fundingReference.awardTitle
Psychobiology of security motivation in an animal model of OCD
en_US
frdr.crdc.code
RDF3010499
en_US
frdr.crdc.group_en
Basic medicine and life sciences
en_US
frdr.crdc.class_en
Neurosciences, medical and physiological and health aspects
en_US
frdr.crdc.field_en
Neurosciences, medical and health and physiological aspects, not elsewhere classified
en_US
frdr.crdc.group_fr
Médecine fondamentale et sciences de la vie
fr_CA
frdr.crdc.class_fr
Neurosciences, aspects médicaux et physiologiques et de la santé
fr_CA
frdr.crdc.field_fr
Neurosciences, aspects médicaux, physiologiques, et de la santé, non classé ailleurs
fr_CA
frdr.crdc.code
RDF1061105
en_US
frdr.crdc.group_en
Biological sciences
en_US
frdr.crdc.class_en
Neurosciences, biological and chemical aspects
en_US
frdr.crdc.field_en
Behavioural neuroscience of learning and memory
en_US
frdr.crdc.group_fr
Sciences biologiques
fr_CA
frdr.crdc.class_fr
Neurosciences, aspects biologiques et chimiques
fr_CA
frdr.crdc.field_fr
Neurosciences comportementales de l'apprentissage et de la mémoire
fr_CA
frdr.crdc.code
RDF5010113
en_US
frdr.crdc.group_en
Psychology and cognitive sciences
en_US
frdr.crdc.class_en
Psychology, social and behavioural aspects
en_US
frdr.crdc.field_en
Psychopathology
en_US
frdr.crdc.group_fr
Psychologie et sciences cognitives
fr_CA
frdr.crdc.class_fr
Psychologie, aspects sociaux et comportementaux
fr_CA
frdr.crdc.field_fr
Psychopathologie
fr_CA
frdr.crdc.code
RDF5010208
en_US
frdr.crdc.group_en
Psychology and cognitive sciences
en_US
frdr.crdc.class_en
Cognitive sciences
en_US
frdr.crdc.field_en
Cognitive behaviour
en_US
frdr.crdc.group_fr
Psychologie et sciences cognitives
fr_CA
frdr.crdc.class_fr
Sciences cognitives
fr_CA
frdr.crdc.field_fr
Comportement cognitif
fr_CA
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