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Project_07 Q18 StudyTitle Probing the role of hormones in compulsive checking: Is the endocrine system necessary for compulsive behavior?
| Description: | This study (Q18) is one of a series of studies performed in the Szechtman lab at McMaster University and deposited in the FRDR public repository as a collection under the name "A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection". This collection as a whole constitutes a big dataset containing raw data objects of video, track, and path plot records of rats exploring for 55 minutes a large testing environment in a standardized paradigm during chronic treatment with psychostimulant drugs; for details of this big dataset see, https://www.frdr-dfdr.ca/repo/collection/szechtmanlab. The historical context for study Q18 was Project_07 entitled: "Probing the role of hormones in compulsive checking". Title of experiment in Q18 was "Effects of hypophysectomy on compulsive checking and cortical dendrites". |
| Authors: | Szechtman, Henry; McMaster University;  0000-0003-3986-4482Dvorkin-Gheva, Anna; McMaster University; 0000-0001-7295-7440Culver, Kirsten E.; McMaster University Waxman, Donna; McMaster University |
| Keywords: | animal model obsessive compulsive disorder OCD compulsive checking behavior exploration locomotion motor activity behavioral sensitization security motivation system male rats Long-Evans open field large testing environment 160x160 cm dopamine receptor agonist chronic treatment with quinpirole (0.5 mg/kg) hypophysectomy hormones dendritic morphology in Cg3 and Par1 repeated injections of saline vehicle video recording digitized track record
plot of routes of locomotion
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repeated testing repeated open field trials per rat 6 trials available 144 number of rats 24 |
| Field of Research: | Biological sciences > Neurosciences, biological and chemical aspects > Behavioural neuroscience of reward and motivation
Basic medicine and life sciences > Neurosciences, medical and physiological and health aspects > Neurosciences, medical and health and physiological aspects, not elsewhere classified
Psychology and cognitive sciences > Psychology, social and behavioural aspects > Psychopathology
Psychology and cognitive sciences > Cognitive sciences > Cognitive behaviour
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| Publication Date: | 2021-07-30 |
| Publisher: | Federated Research Data Repository / dépôt fédéré de données de recherche |
| Funder: | Canadian Institutes of Health Research (CIHR); Dopamine, movements, motion and behavior; MT-12852 Canadian Institutes of Health Research (CIHR); Dopamine, movements, motion and behaviour: Animal model of OCD; MOP-64424 Natural Sciences and Engineering Research Council of Canada (NSERC); RGPIN A0544 |
| URI: | https://doi.org/10.20383/102.0444 |
| Related Identifiers: |
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| Geographic Coverage: | Place Name Health Sciences Centre, McMaster University City Hamilton Province / Province / Territory Ontario Territory Country Canada |
| Geographic Point: | Latitude 43.25978 Longitude -79.91763 |
| Appears in Collections: | A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection |
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Access to this dataset is subject to the following terms:
Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
Citation
Szechtman, H., Dvorkin-Gheva, A., Culver, K., Waxman, D. (2021). Project_07 Q18 StudyTitle Probing the role of hormones in compulsive checking: Is the endocrine system necessary for compulsive behavior?. Federated Research Data Repository. https://doi.org/10.20383/102.0444
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