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Project_09 Q29 StudyTitle Probing the environmental modulation of sensitization and compulsive checking: influence of a small ledge around OF
| Description: | This study (Q29) is one of a series of studies performed in the Szechtman lab at McMaster University and deposited in the FRDR public repository as a collection under the name "A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection". This collection as a whole constitutes a big dataset containing raw data objects of video, track, and path plot records of rats exploring for 55 minutes a large testing environment in a standardized paradigm during chronic treatment with psychostimulant drugs; for details of this big dataset see, https://www.frdr-dfdr.ca/repo/collection/szechtmanlab. The historical context for study Q29 was Project_09 entitled: "Probing the environmental modulation of sensitization and compulsive checking". Title of the experiment in Q29 was "Effect of a small ledge on open field on the development of sensitization and compulsive checking". Study Q29 was also part of a second project, Project_02 entitled: "Probing the neurochemistry of sensitization and compulsive checking", where title of the experiment was "Effect of CP809101 (5HT2C agonist) on the expression of sensitization and compulsive checking in an open field bordered by a low ledge". Note that Q29 dataset does not have the raw data object, path plot of routes of locomotion. |
| Authors: | Szechtman, Henry; McMaster University;  0000-0003-3986-4482Dvorkin-Gheva, Anna; McMaster University; 0000-0001-7295-7440 |
| Keywords: | animal model obsessive compulsive disorder OCD compulsive checking behavior exploration locomotion motor activity behavioral sensitization security motivation system male rats Long-Evans open field large testing environment 160x160 cm modified open field 160x160x60 cm table with a 5 cm high Plexiglas border at edges dopamine receptor agonist chronic treatment with quinpirole (0.5 mg/kg) serotonin receptor agonist acute treatment with 5HT2C agonist CP809101 (7.5 mg/kg) repeated injections of saline vehicle video recording
digitized track record
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plot of routes of locomotion repeated testing repeated trials per rat 13 trials available 208 number of rats 16 |
| Field of Research: | Biological sciences > Neurosciences, biological and chemical aspects > Behavioural neuroscience of reward and motivation
Basic medicine and life sciences > Neurosciences, medical and physiological and health aspects > Neurosciences, medical and health and physiological aspects, not elsewhere classified
Psychology and cognitive sciences > Psychology, social and behavioural aspects > Psychopathology
Psychology and cognitive sciences > Cognitive sciences > Cognitive behaviour
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| Publication Date: | 2021-07-13 |
| Publisher: | Federated Research Data Repository / dépôt fédéré de données de recherche |
| Funder: | Canadian Institutes of Health Research (CIHR); Dopamine, movements, motion and behaviour: Animal model of OCD; MOP-64424 |
| URI: | https://doi.org/10.20383/102.0435 |
| Related Identifiers: |
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| Geographic Coverage: | Place Name Health Sciences Centre, McMaster University City Hamilton Province / Province / Territory Ontario Territory Country Canada |
| Geographic Point: | Latitude 43.25978 Longitude -79.91763 |
| Appears in Collections: | A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection |
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Access to this dataset is subject to the following terms:
Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
Citation
Szechtman, H., Dvorkin-Gheva, A. (2021). Project_09 Q29 StudyTitle Probing the environmental modulation of sensitization and compulsive checking: influence of a small ledge around OF. Federated Research Data Repository. https://doi.org/10.20383/102.0435
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