Field
Value
Language
dc.contributor.author
Szechtman, Henry
datacite.creator.affiliationIdentifier
https://ror.org/02fa3aq29
en_US
datacite.creator.affiliation
McMaster University
en_US
datacite.creator.nameIdentifier
https://orcid.org/0000-0003-3986-4482
en_US
dc.contributor.author
Dvorkin-Gheva, Anna
datacite.creator.affiliationIdentifier
https://ror.org/02fa3aq29
en_US
datacite.creator.affiliation
McMaster University
en_US
datacite.creator.nameIdentifier
https://orcid.org/0000-0001-7295-7440
en_US
dc.contributor.author
McMurran, Thomas J.A.
datacite.creator.affiliationIdentifier
https://ror.org/02fa3aq29
en_US
datacite.creator.affiliation
McMaster University
en_US
datacite.creator.nameIdentifier
en_US
dc.date.accessioned
2021-07-20T15:41:24Z
dc.date.available
2021-07-20T15:41:24Z
dc.date.issued
2021-07-20
dc.identifier.uri
https://www.frdr-dfdr.ca/repo/dataset/0b2a368e-9360-4be1-bf0d-ca593a380367
dc.identifier.uri
https://doi.org/10.20383/102.0436
dc.description
This study (Q28) is one of a series of studies performed in the Szechtman lab at McMaster University and deposited in the FRDR public repository as a collection under the name "A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection". This collection as a whole constitutes a big dataset containing raw data objects of video, track, and path plot records of rats exploring for 55 minutes a large testing environment in a standardized paradigm during chronic treatment with psychostimulant drugs; for details of this big dataset see, https://www.frdr-dfdr.ca/repo/collection/szechtmanlab.
The historical context for study Q28 was Project_01 entitled: "Probing the neural circuit mediating sensitization and compulsive checking". This project had two separate studies, designated as Q28OFC1 and Q28OFC2. The title of study Q28OFC1 was "Probing the neural circuit mediating sensitization and compulsive checking: role of the lateral orbitofrontal cortex (OFC) on development" and the title of study Q28OFC2 was "Probing the neural circuit mediating sensitization and compulsive checking: role of the lateral orbitofrontal cortex (OFC) on expression". Title of experiment in Q28OFC1 was "Effect of an NMDA lesion of the OFC on the development of sensitization and compulsive checking" and title of experiment in Q28OFC2 was "Effect of an NMDA lesion of the OFC on the expression of sensitization and compulsive checking". For the development study (Q28OFC1), rats received a lesion targeted at the OFC and the effect of this lesion on the induction of compulsive checking in our standard paradigm was measured. For the expression study (Q28OFC2), rats received our standard treatment to induce compulsive checking and then received a lesion targeted at the OFC and the effect of this lesion on the expression of compulsive checking was measured.
This dataset has the same Design and Procedure as dataset deposits for StudyID Q26 doi:10.20383/102.0438 and StudyID Q25 doi:10.20383/102.0439
en_US
dc.publisher
Federated Research Data Repository / dépôt fédéré de données de recherche
dc.rights
Creative Commons Attribution 4.0 International (CC BY 4.0)
en_US
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
en_US
dc.subject
animal model
en_US
dc.subject
obsessive compulsive disorder
en_US
dc.subject
OCD
en_US
dc.subject
compulsive checking behavior
en_US
dc.subject
exploration
en_US
dc.subject
locomotion
en_US
dc.subject
motor activity
en_US
dc.subject
behavioral sensitization
en_US
dc.subject
security motivation system
en_US
dc.subject
male rats Long-Evans
en_US
dc.subject
open field
en_US
dc.subject
large testing environment 160x160 cm
en_US
dc.subject
dopamine receptor agonist
en_US
dc.subject
chronic treatment with quinpirole (0.5 mg/kg)
en_US
dc.subject
lateral orbitofrontal cortex (OFC) NMDA lesion
en_US
dc.subject
lesion effect on development of response to repeated treatment
en_US
dc.subject
lesion effect on expression of established behavior
en_US
dc.subject
repeated injections of saline vehicle
en_US
dc.subject
video recording
en_US
dc.subject
digitized track record
en_US
dc.subject
plot of routes of locomotion
en_US
dc.subject
repeated testing
en_US
dc.subject
repeated trials per rat 14
en_US
dc.subject
trials available 1551
en_US
dc.subject
number of rats 112
en_US
dc.title
Project_01 Q28 StudyTitle Probing the neural circuit mediating sensitization and compulsive checking: role of the lateral orbitofrontal cortex (OFC) on development, and, on expression
en_US
globus.shared_endpoint.name
f163c1b3-9c88-42f6-a7bb-5839ed6c4063
globus.shared_endpoint.path
/11/published/publication_431/
datacite.publicationyear
2021
datacite.date.Collected
2007-05-10/2007-07-13
datacite.date.Collected
2007-07-16/2007-08-31
datacite.resourcetype
Dataset
en_US
datacite.relatedidentifier.IsCitedBy
https://doi.org/10.1093/gigascience/giac092
datacite.relatedidentifier.Cites
https://doi.org/10.1037/0735-7044.112.6.1475
datacite.relatedidentifier.Cites
https://doi.org/10.1016/j.jneumeth.2003.10.013
datacite.relatedidentifier.IsSupplementTo
https://doi.org/10.1111/j.1460-9568.2010.07398.x
datacite.relatedidentifier.IsSupplementTo
https://www.ibnsconnect.org/assets/docs/pastprograms/ibnsprogram2009final.pdf
datacite.relatedidentifier.IsSupplementTo
https://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=2fd47965-8611-4f34-96fc-c683f4b84874&cKey=39a2326e-38ac-40fc-b6d1-e2e7cb1aa0c1&mKey=%7b081F7976-E4CD-4F3D-A0AF-E8387992A658%7d
datacite.relatedidentifier.IsSupplementTo
http://discovery.mcmaster.ca/iii/encore/record/C__Rb1766025
datacite.relatedidentifier.IsSupplementedBy
https://doi.org/10.1016/j.bbr.2006.01.024
datacite.relatedidentifier.IsSupplementedBy
https://doi.org/10.1097/FBP.0000000000000112
datacite.relatedidentifier.Continues
https://doi.org/10.20383/102.0439
datacite.relatedidentifier.Continues
https://doi.org/10.20383/102.0438
datacite.relatedidentifier.IsPartOf
https://www.frdr-dfdr.ca/repo/collection/szechtmanlab
datacite.geolocation.geolocationPoint
43.25978 -79.91763
datacite.geolocation.geolocationPlace
Health Sciences Centre, McMaster University;Hamilton;Ontario;Canada
datacite.fundingReference.funderName
Canadian Institutes of Health Research (CIHR)
en_US
datacite.fundingReference.awardNumber
MOP-64424
en_US
datacite.fundingReference.awardTitle
Dopamine, movements, motion and behaviour: Animal model of OCD
en_US
frdr.crdc.code
RDF1061106
en_US
frdr.crdc.group_en
Biological sciences
en_US
frdr.crdc.class_en
Neurosciences, biological and chemical aspects
en_US
frdr.crdc.field_en
Behavioural neuroscience of reward and motivation
en_US
frdr.crdc.group_fr
Sciences biologiques
fr_CA
frdr.crdc.class_fr
Neurosciences, aspects biologiques et chimiques
fr_CA
frdr.crdc.field_fr
Neurosciences comportementales de la récompense et de la motivation
fr_CA
frdr.crdc.code
RDF3010499
en_US
frdr.crdc.group_en
Basic medicine and life sciences
en_US
frdr.crdc.class_en
Neurosciences, medical and physiological and health aspects
en_US
frdr.crdc.field_en
Neurosciences, medical and health and physiological aspects, not elsewhere classified
en_US
frdr.crdc.group_fr
Médecine fondamentale et sciences de la vie
fr_CA
frdr.crdc.class_fr
Neurosciences, aspects médicaux et physiologiques et de la santé
fr_CA
frdr.crdc.field_fr
Neurosciences, aspects médicaux, physiologiques, et de la santé, non classé ailleurs
fr_CA
frdr.crdc.code
RDF5010113
en_US
frdr.crdc.group_en
Psychology and cognitive sciences
en_US
frdr.crdc.class_en
Psychology, social and behavioural aspects
en_US
frdr.crdc.field_en
Psychopathology
en_US
frdr.crdc.group_fr
Psychologie et sciences cognitives
fr_CA
frdr.crdc.class_fr
Psychologie, aspects sociaux et comportementaux
fr_CA
frdr.crdc.field_fr
Psychopathologie
fr_CA
frdr.crdc.code
RDF5010208
en_US
frdr.crdc.group_en
Psychology and cognitive sciences
en_US
frdr.crdc.class_en
Cognitive sciences
en_US
frdr.crdc.field_en
Cognitive behaviour
en_US
frdr.crdc.group_fr
Psychologie et sciences cognitives
fr_CA
frdr.crdc.class_fr
Sciences cognitives
fr_CA
frdr.crdc.field_fr
Comportement cognitif
fr_CA
Appears in Collections: