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Local field potential in the medial prefrontal cortex of 5xFAD mice during exposure to social and non-social odour stimuli

Description: This dataset contains local field potential (LFP) data collected from the medial prefrontal cortex of transgenic 5xFAD females and males and wild-type controls (n = 7 females/group, 6 males/group) during exposure to social and non-social olfactory stimuli, as well as VOC level readings from the testing chamber during stimulus presentation. LFP data consists of 15s recordings from a single channel sampled at ~500Hz; zero time is given as the time at which VOC levels (recorded every 250msec) began to increase from baseline. Data also contains artifact-free periods (2s or longer, taken from the 15s period) that were used for final data analysis in the publication. All recordings were taken from the prelimbic or anterior cingulate cortices; recording locations (based on the Allen Mouse Brain Atlas) are provided for each subject.
Notes: Kosel, F., Hartley, M. R., & Franklin, T. B. (2024). Aberrant Cortical Activity in 5xFAD Mice in Response to Social and Non-Social Olfactory Stimuli. Journal of Alzheimer's disease : JAD, 97(2), 659–677.
Authors: Kosel, Filip; Dalhousie University; ORCID iD 0000-0002-7488-684X
Franklin, Tamara B; Dalhousie University; ORCID iD 0000-0002-8733-8228
Hartley, Mackenzie Rae; Dalhousie University; ORCID iD 0009-0007-9653-2990
Keywords: local field potential
medial prefrontal cortex
mouse model
familial Alzheimer’s disease (FAD)
Field of Research: 
Basic medicine and life sciences
Neurosciences, medical and physiological and health aspects
Neurological disorders (except neuromuscular diseases)
Publication Date: 2024-03-13
Publisher: Federated Research Data Repository / dépôt fédéré de données de recherche
Related Identifiers: 
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Access to this dataset is subject to the following terms:
Creative Commons Attribution 4.0 International (CC BY 4.0)
Kosel, F., Franklin, T., Hartley, M. (2024). Local field potential in the medial prefrontal cortex of 5xFAD mice during exposure to social and non-social odour stimuli. Federated Research Data Repository.