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Project_09 Q27 StudyTitle Probing the environmental modulation of sensitization and compulsive checking: effect of having a different environment for the development and the expression of behavior under QNP
Description: | This study (Q27) is one of a series of studies performed in the Szechtman lab at McMaster University and deposited in the FRDR public repository as a collection under the name "A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection". This collection as a whole constitutes a big dataset containing raw data objects of video, track, and path plot records of rats exploring for 55 minutes a large testing environment in a standardized paradigm during chronic treatment with psychostimulant drugs; for details of this big dataset see, https://www.frdr-dfdr.ca/repo/collection/szechtmanlab. The historical context for study Q27 was Project_09 entitled: "Probing the environmental modulation of sensitization and compulsive checking". Title of experiment in Q27 was "Effect of sensitization in activity chambers or in the home cage on performance of compulsive checking in the open field". |
Authors: | Szechtman, Henry; McMaster University; https://orcid.org/0000-0003-3986-4482 ![]() Dvorkin-Gheva, Anna; McMaster University; https://orcid.org/0000-0001-7295-7440 ![]() |
Keywords: | animal model obsessive compulsive disorder OCD compulsive checking behavior exploration locomotion motor activity behavioral sensitization security motivation system male rats Long-Evans open field large testing environment 160x160 cm locomotor activity chambers 40x40x35 cm dopamine receptor agonist chronic treatment with quinpirole (0.5 mg/kg) contextual effects on sensitization and compulsive checking environment-dependent and environment-independent effects of quinpirole repeated injections of saline vehicle video recording digitized track record
plot of routes of locomotion
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repeated testing repeated trials per rat 11 trials available 320 number of rats 70 |
Field of Research: | Biological sciences > Neurosciences, biological and chemical aspects > Behavioural neuroscience of reward and motivation
Basic medicine and life sciences > Neurosciences, medical and physiological and health aspects > Neurosciences, medical and health and physiological aspects, not elsewhere classified
Psychology and cognitive sciences > Psychology, social and behavioural aspects > Psychopathology
Psychology and cognitive sciences > Cognitive sciences > Cognitive behaviour
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Date: | 2021-07-23 |
Publisher: | Federated Research Data Repository / dépôt fédéré de données de recherche |
URI: | https://doi.org/10.20383/102.0437 |
Related Identifiers: |
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Geographic Coverage: | Place Name Health Sciences Centre, McMaster University City Hamilton Province / Province / Territory Ontario Territory Country Canada |
Geographic Point: | Latitude 43.25978 Longitude -79.91763 |
Appears in Collections: | A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection |
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Access to this dataset is subject to the following terms:
Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
Citation
Szechtman, H. , Dvorkin-Gheva, A. (2021) Project_09 Q27 StudyTitle Probing the environmental modulation of sensitization and compulsive checking: effect of having a different environment for the development and the expression of behavior under QNP. Federated Research Data Repository. https://doi.org/10.20383/102.0437