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Home cage based motor learning platform PiPaw2.0

Description: This data repository contains detailed information from a study using the PiPaw2.0 system, an advanced behavioral testing framework for mice. The system includes a modified mouse home cage with a 3D-printed training module, equipped with a nose-poke port, water spout, and a pivotable lever. It features a high-resolution encoder for tracking lever movements and an RFID system for identifying individual mice. The task involves a 'hold task' where mice are trained to pull and hold a lever within a specified range to receive water rewards. Data collected over two months includes task performance metrics, lever trajectory data, and video recordings of trials. The repository contains the data collected from B6J.zQ175 KI (zQ175) mouse model of Huntington Disease and Wild-type (WT) littermates grouped housed in the automated homecages.
Notes: Item exited embargo and became publicly available on 2024-09-24
Authors: Ramandi, Daniel; University of British Columbia; ORCID iD 0000-0003-2995-154X
Wang, Zefang; University of British Columbia; ORCID iD 0009-0006-9129-6821
Murphy, Timothy; University of British Columbia; ORCID iD 0000-0002-0093-4490
Han, Brian; University of British Columbia; ORCID iD 0009-0009-9348-6823
Raymond, Lynn; University of British Columbia; ORCID iD 0000-0002-8610-1042
Keywords: motor learning
homecage
huntington disease
behavior
skill learning
bahavior modeling
mouse
Field of Research: 
Biological sciences
>
Neurosciences, biological and chemical aspects
>
Behavioural neuroscience of learning and memory
Publication Date: 2024-09-24
Publisher: Federated Research Data Repository / dépôt fédéré de données de recherche
Funder: Canadian Institutes of Health Research; PJT178043
URI: https://doi.org/10.20383/103.0869
Appears in Collections:UBC Brain Circuits

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Access to this dataset is subject to the following terms:
Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
Citation
Ramandi, D., Wang, Z., Murphy, T., Han, B., Raymond, L. (2024). Home cage based motor learning platform PiPaw2.0. Federated Research Data Repository. https://doi.org/10.20383/103.0869