Field
Value
Language
dc.contributor.author
Rahman, Naila
datacite.creator.affiliationIdentifier
https://ror.org/02grkyz14
en_US
datacite.creator.affiliation
Western University
en_US
datacite.creator.nameIdentifier
en_US
dc.contributor.author
Xu, Kathy
datacite.creator.affiliationIdentifier
https://ror.org/02grkyz14
en_US
datacite.creator.affiliation
Western University
en_US
datacite.creator.nameIdentifier
en_US
dc.contributor.author
Budde, Matthew D.
datacite.creator.affiliationIdentifier
https://ror.org/00qqv6244
en_US
datacite.creator.affiliation
Medical College of Wisconsin
en_US
dc.contributor.author
Brown, Arthur
datacite.creator.affiliationIdentifier
https://ror.org/02grkyz14
en_US
datacite.creator.affiliation
Western University
en_US
dc.contributor.author
Baron, Corey A.
datacite.creator.affiliationIdentifier
https://ror.org/02grkyz14
en_US
datacite.creator.affiliation
Western University
en_US
dc.date.accessioned
2022-07-07T06:26:45Z
dc.date.available
2022-07-07T06:26:45Z
dc.date.issued
2022-07-07
dc.identifier.uri
https://www.frdr-dfdr.ca/repo/dataset/9ea832ad-7f36-4e37-b7ac-47167c0001c1
dc.identifier.uri
https://doi.org/10.20383/103.0594
dc.description
Multimodal microstructural MRI has shown increased sensitivity and specificity to changes in various brain disease and injury models in the preclinical setting. Here, we present an in vivo longitudinal dataset, acquired as control data and to investigate microstructural changes in the healthy mouse brain. The dataset consists of structural T2-weighted imaging, magnetization transfer ratio and saturation imaging, and advanced quantitative diffusion MRI (dMRI) methods. The dMRI methods include oscillating gradient spin echo (OGSE) dMRI and microscopic anisotropy (μA) dMRI, which provide additional insight by increasing sensitivity to smaller spatial scales and disentangling fiber orientation dispersion from true microstructural changes, respectively. The technical skills required to analyze microstructural MRI data are complex and include MRI sequence development, acquisition, and computational neuroimaging expertise. Here, we share unprocessed and preprocessed data, and scalar maps of quantitative MRI metrics. We envision utility of this dataset in the microstructural MRI field to develop and test biophysical models, methods that model temporal brain dynamics, and different registration and preprocessing pipelines.
en_US
dc.publisher
Federated Research Data Repository / dépôt fédéré de données de recherche
dc.rights
Creative Commons Attribution 4.0 International (CC BY 4.0)
en_US
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
en_US
dc.subject
Diffusion MRI
en_US
dc.subject
Magnetization Transfer MRI
en_US
dc.subject
Microstructure
en_US
dc.subject
Longitudinal in vivo Imaging
en_US
dc.subject
Multimodal MRI
en_US
dc.subject
Preclinical
en_US
dc.subject
Rodent brain
en_US
dc.title
A longitudinal microstructural MRI dataset in healthy C57Bl/6 mice at 9.4 Tesla
en_US
globus.shared_endpoint.name
f163c1b3-9c88-42f6-a7bb-5839ed6c4063
globus.shared_endpoint.path
/1/published/publication_589/
frdr.preservation.status
Version 1: AIP generation and transfer successful
Version 2: AIP generation and transfer successful
Version 3: AIP generation and transfer successful
frdr.preservation.datetime
Version 1
AIP #1: 2024-02-14
AIP #2: 2024-02-21
AIP #3: 2024-02-21
AIP #4: 2024-02-29
AIP #5: 2024-03-01
frdr.preservation.datetime
Version 2
AIP #1: 2024-03-19
AIP #2: 2024-03-19
AIP #3: 2024-03-19
AIP #4: 2024-03-19
AIP #5: 2024-03-19
frdr.preservation.datetime
Version 3
AIP #1: 2024-03-19
AIP #2: 2024-03-19
AIP #3: 2024-03-20
AIP #4: 2024-03-20
AIP #5: 2024-03-20
AIP #6: 2024-03-20
AIP #7: 2024-03-20
datacite.publicationyear
2022
datacite.contributor.DataCollector
Naila Rahman
datacite.contributor.Supervisor
Corey A. Baron
datacite.contributor.Other
Kathy Xu
datacite.contributor.Other
Matthew D. Budde
datacite.contributor.Other
Arthur Brown
datacite.date.Collected
2020-11-26/2021-09-04
datacite.resourcetype
Dataset
en_US
datacite.relatedidentifier.IsSupplementedBy
https://gitlab.com/cfmm/pipelines/mouse_dmri_MT_dicomTOscalarMaps
datacite.geolocation.geolocationPlace
Robarts Research Institute, University of Western Ontario;London;Ontario;Canada
datacite.fundingReference.funderIdentifier
en_US
datacite.fundingReference.funderName
Canada First Research Excellence Fund
en_US
datacite.fundingReference.awardNumber
en_US
datacite.fundingReference.awardTitle
BrainsCAN
en_US
datacite.fundingReference.funderIdentifier
en_US
datacite.fundingReference.funderName
New Frontiers in Research Fund
en_US
datacite.fundingReference.awardNumber
NFRFE-2018-01290
en_US
datacite.fundingReference.awardTitle
en_US
datacite.fundingReference.funderIdentifier
datacite.fundingReference.funderName
Natural Sciences and Engineering Research Council of Canada
en_US
datacite.fundingReference.awardNumber
datacite.fundingReference.awardTitle
Canada Graduate Scholarships - Master’s Program
datacite.fundingReference.funderIdentifier
datacite.fundingReference.funderName
Ontario Graduate Scholarship (OGS) Program
en_US
datacite.fundingReference.awardNumber
datacite.fundingReference.awardTitle
frdr.crdc.code
RDF3010402
en_US
frdr.crdc.group_en
Basic medicine and life sciences
en_US
frdr.crdc.class_en
Neurosciences, medical and physiological and health aspects
en_US
frdr.crdc.field_en
Central nervous system
en_US
frdr.crdc.group_fr
Médecine fondamentale et sciences de la vie
fr_CA
frdr.crdc.class_fr
Neurosciences, aspects médicaux et physiologiques et de la santé
fr_CA
frdr.crdc.field_fr
Système nerveux central
fr_CA
datacite.description.other
This dataset is made available under a CC-BY license <https://creativecommons.org/licenses/by/4.0/>, however, the file code_scidata_paper/niiCombDiffAve/MPdenoising.m has an additional non-commercial clause and may only be used or copied for non-commercial research. Please cite Jelle Veraart (2016) and see the file header for its full terms of use. In addition, the Turone Mouse Brain Template and Atlas in Registration/atlas/TMBTA_Brain_Template and Registration/atlas/TMBTA_Brain_Labels may only be used for non-commercial purposes. Please cite David André Barrière (2019) and visit https://www.nitrc.org/projects/tmbta_2019/ in the NeuroImaging Tools and Resources Collaboratory for full terms of use.