Field
Value
Language
dc.contributor.author
Szechtman, Henry
datacite.creator.affiliationIdentifier
https://ror.org/02fa3aq29
en_US
datacite.creator.affiliation
McMaster University
en_US
datacite.creator.nameIdentifier
https://orcid.org/0000-0003-3986-4482
en_US
dc.contributor.author
Dvorkin-Gheva, Anna
datacite.creator.affiliationIdentifier
https://ror.org/02fa3aq29
en_US
datacite.creator.affiliation
McMaster University
en_US
datacite.creator.nameIdentifier
https://orcid.org/0000-0001-7295-7440
en_US
dc.date.accessioned
2021-06-21T15:52:35Z
dc.date.available
2021-06-21T15:52:35Z
dc.date.issued
2021-06-21
dc.identifier.uri
https://www.frdr-dfdr.ca/repo/dataset/9f6c0cbd-a2a4-48ed-9802-3330833eeb69
dc.identifier.uri
https://doi.org/10.20383/102.0417
dc.description
This study (Q48) is one of a series of studies performed in the Szechtman lab at McMaster University and deposited in the FRDR public repository as a collection under the name "A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection". This collection as a whole constitutes a big dataset containing RAWDATA objects (video, track, path plot and EthoVision files) of rats exploring for 55 minutes a large testing environment in a standardized paradigm during chronic treatment with psychostimulant drugs; for details of this big dataset see, https://www.frdr-dfdr.ca/repo/collection/szechtmanlab.
The historical context for study Q48 was Project_11 entitled: "Probing for biological markers of the pathogenesis of compulsive checking". The particular question investigated in Q48 was whether the developments of compulsive checking and locomotor sensitization were accompanied by changes in gene expression and microbiome composition. Findings of gut microbiota changes during induction of compulsive checking and sensitization to quinpirole had been published (https://doi.org/10.1097/FBP.0000000000000363). Results of mRNA expression were inconclusive and not published; raw data are included in sub-folder 11_SPSS_savMasterFiles.
Aside the RAWDAA objects (video, track, path plot, and EthoVision files) provided by every study in the Szechtman Lab Collection, study Q48 deposit contains derived data for measures of compulsive checking and locomotion as well as files that document specifics of the study, as described in the README.txt file.
en_US
dc.publisher
Federated Research Data Repository / dépôt fédéré de données de recherche
dc.rights
Creative Commons Attribution 4.0 International (CC BY 4.0)
en_US
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
en_US
dc.subject
animal model
en_US
dc.subject
obsessive compulsive disorder
en_US
dc.subject
OCD
en_US
dc.subject
compulsive checking behavior
en_US
dc.subject
exploration
en_US
dc.subject
locomotion
en_US
dc.subject
motor activity
en_US
dc.subject
behavioral sensitization
en_US
dc.subject
security motivation system
en_US
dc.subject
male rats Long-Evans
en_US
dc.subject
open field
en_US
dc.subject
large testing environment 160x160 cm
en_US
dc.subject
dopamine receptor agonist
en_US
dc.subject
chronic treatment with quinpirole (0.25 mg/kg)
en_US
dc.subject
repeated injections of saline vehicle
en_US
dc.subject
video recording
en_US
dc.subject
digitized track record
en_US
dc.subject
plot of routes of locomotion
en_US
dc.subject
repeated testing
en_US
dc.subject
number of repeated trials per rat 9
en_US
dc.subject
total trials from study 281
en_US
dc.subject
number of rats in study 31
en_US
dc.subject
energy metabolism
en_US
dc.subject
microbiome
en_US
dc.title
Project_11 Q48 StudyTitle Probing for biological markers of the pathogenesis of compulsive checking: mRNA expression and changes in gut microbiota
en_US
globus.shared_endpoint.name
f163c1b3-9c88-42f6-a7bb-5839ed6c4063
globus.shared_endpoint.path
/11/published/publication_412/
datacite.publicationyear
2021
datacite.contributor.ProjectManager
Sakic, Boris
datacite.date.Collected
2015-11-02/2015-12-15
datacite.resourcetype
Dataset
en_US
datacite.relatedidentifier.IsCitedBy
https://doi.org/10.1093/gigascience/giac092
datacite.relatedidentifier.IsSupplementedBy
https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA414436
datacite.relatedidentifier.IsPartOf
https://www.frdr-dfdr.ca/repo/collection/szechtmanlab
datacite.relatedidentifier.IsSourceOf
https://doi.org/10.1097/FBP.0000000000000363
datacite.geolocation.geolocationPoint
43.25978 -79.91763
datacite.geolocation.geolocationPlace
Health Sciences Centre U58, McMaster University;Hamilton;Ontario;Canada
datacite.geolocation.geolocationPlace
Health Sciences Centre U59, McMaster University;Hamilton;Ontario;Canada
datacite.geolocation.geolocationPlace
Health Sciences Centre 4N7, McMaster University;Hamilton;Ontario;Canada
datacite.fundingReference.funderName
Ontario Mental Health Foundation (OMHF)
en_US
datacite.fundingReference.awardNumber
Type A Grant
en_US
datacite.fundingReference.awardTitle
Psychobiology of security motivation in an animal model of OCD
en_US
frdr.crdc.code
RDF3010499
en_US
frdr.crdc.group_en
Basic medicine and life sciences
en_US
frdr.crdc.class_en
Neurosciences, medical and physiological and health aspects
en_US
frdr.crdc.field_en
Neurosciences, medical and health and physiological aspects, not elsewhere classified
en_US
frdr.crdc.group_fr
Médecine fondamentale et sciences de la vie
fr_CA
frdr.crdc.class_fr
Neurosciences, aspects médicaux et physiologiques et de la santé
fr_CA
frdr.crdc.field_fr
Neurosciences, aspects médicaux, physiologiques, et de la santé, non classé ailleurs
fr_CA
frdr.crdc.code
RDF1061106
en_US
frdr.crdc.group_en
Biological sciences
en_US
frdr.crdc.class_en
Neurosciences, biological and chemical aspects
en_US
frdr.crdc.field_en
Behavioural neuroscience of reward and motivation
en_US
frdr.crdc.group_fr
Sciences biologiques
fr_CA
frdr.crdc.class_fr
Neurosciences, aspects biologiques et chimiques
fr_CA
frdr.crdc.field_fr
Neurosciences comportementales de la récompense et de la motivation
fr_CA
frdr.crdc.code
RDF5010113
en_US
frdr.crdc.group_en
Psychology and cognitive sciences
en_US
frdr.crdc.class_en
Psychology, social and behavioural aspects
en_US
frdr.crdc.field_en
Psychopathology
en_US
frdr.crdc.group_fr
Psychologie et sciences cognitives
fr_CA
frdr.crdc.class_fr
Psychologie, aspects sociaux et comportementaux
fr_CA
frdr.crdc.field_fr
Psychopathologie
fr_CA
frdr.crdc.code
RDF5010208
en_US
frdr.crdc.group_en
Psychology and cognitive sciences
en_US
frdr.crdc.class_en
Cognitive sciences
en_US
frdr.crdc.field_en
Cognitive behaviour
en_US
frdr.crdc.group_fr
Psychologie et sciences cognitives
fr_CA
frdr.crdc.class_fr
Sciences cognitives
fr_CA
frdr.crdc.field_fr
Comportement cognitif
fr_CA
Appears in Collections:
