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erythroSight: Open-access image dataset of blood cells from individuals with sickle cell disease and/or beta-thalassemia or without known hemaglobinopathies, captured using automated microscope Octopi

Description: This dataset contains over 300,000 microscopic images of blood cells from 138 participants in Nepal and Canada, captured using automated microscope Octopi. The images (0.9 mm by 0.9 mm) were captured for research studies in Nepalgunj, Nepal and Vancouver, Canada to evaluate low-cost tools for detecting sickle cell disease and beta-thalassemia. The dataset includes raw image pairs (left and right half illuminated images), processed images (differential phase contrast images), cell segmentation outlines, and morphological characterization of cells. The majority of images are captured 2 hours after sample preparation of the sickling test at room temperature, while other configurations (such as other time instances, different temperature settings, time series data) are also included.
Authors: Shrestha, Pranav; University of British Columbia; ORCID iD 0000-0003-2533-2776
Li, Hongquan; Stanford University; ORCID iD 0000-0002-3668-5772
Prakash, Manu; Stanford University; ORCID iD 0000-0002-8046-8388
Merkeley, Hayley; University of British Columbia; ORCID iD 0009-0006-1964-7746
Kapoor, Videsh; University of British Columbia; ORCID iD 0000-0002-1040-3394
Pande, Rajan; Bheri Hospital; ORCID iD 0000-0001-9328-5145
Stoeber, Boris; University of British Columbia; ORCID iD 0000-0003-0230-238X
Keywords: Red blood cells
Erythrocyte
Microscopy
Sickle cell disease
Sickle cell trait
Beta-thalassemia
Octopi
Automated microscope
Hematology
Hematopathology
Biomedical imaging
β-thalassemia
Field of Research: 
Medical and biomedical engineering
>
Medical and biomedical engineering
>
Medical and biomedical engineering, not elsewhere classified

Clinical medicine
>
Cardiorespiratory medicine and hematology
>
Hematology

Medical biotechnology
>
Medical biotechnology
>
Medical biotechnology diagnostics (including biosensors)

Mechanical engineering
>
Other mechanical engineering
>
Other mechanical engineering, not elsewhere classified
Publication Date: 2024-09-18
Publisher: Federated Research Data Repository / dépôt fédéré de données de recherche
Funder: University of British Columbia; AWD-017004
University of British Columbia; AWD-023617 VPHEALTH 2023
Canada Research Chairs; CRC-2017-00041
URI: https://doi.org/10.20383/103.0916
Related Identifiers: 
This dataset is a supplement to

This dataset is a supplement to

This dataset is a supplement to

This dataset is supplemented by
Geographic Coverage: 
Place Name
Mount Sagarmatha Polyclinic and Diagnostic Center
City
Nepalgunj
Province / Territory / State
Bheri Zone/ Province no-5
Country
Nepal

Place Name
BC Children's Hospital
City
Vancouver
Province /
Province / Territory
British Columbia
Territory
 
Country
Canada

Place Name
St. Paul's Hospital
City
Vancouver
Province /
Province / Territory
British Columbia
Territory
 
Country
Canada

Files in Dataset 
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Access to this dataset is subject to the following terms:
Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
Citation
Shrestha, P., Li, H., Prakash, M., Merkeley, H., Kapoor, V., Pande, R., Stoeber, B. (2024). erythroSight: Open-access image dataset of blood cells from individuals with sickle cell disease and/or beta-thalassemia or without known hemaglobinopathies, captured using automated microscope Octopi. Federated Research Data Repository. https://doi.org/10.20383/103.0916